Thinning Post-CXL: How was it managed?

  • A 21-year-old male came with complaints of blurring of vision with a history of eye rubbing. He had bilateral keratoconus, worse in the left eye than the right.

  • Corneal topography & Pentacam examinations showed keratoconus in both eyes, more advanced in the left. With a central corneal thickness of 465microns, patient underwent Corneal Collagen Cross Linking in the left eye first which was the worse eye. He underwent the conventional Dresden protocol.

  • Over the next few years, we could see progressive thinning and fluctuation in his pachymetry and progressive flattening in his keratometry.

  • He was advised use of Rose K lenses as well as deep anterior lamellar keratoplasty. But he was not keen on both.

  • Months later, the patient presented with blurring of vision in the left eye.

  • He said dust went inside his left eye and he rubbed it after which his vision had become blurry.

  • This trivial trauma had caused a corneal perforation confirmed by Seidel’s test and AS-OCT confirmed a corneal perforation

  • Immediate tectonic temporization was done using cyanoacrylate glue and a bandage contact lens

  • Once the eye stabilized, A deep anterior lamellar keratoplasty was performed for visual rehabilitation

  • Patient is doing well with a vision of 6/9 at present

  • This case is a clear example of how the effects—and limitations—of corneal cross-linking can declare themselves many years after the procedure

  • It underscores the importance of long-term surveillance, including regular follow-up with serial Pentacam imaging, and continuous reinforcement of behavioural counselling, particularly strict avoidance of eye rubbing

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Image from Rajan Eye Care Hospital

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Bubble behind the iris: What do we do?