Cyanoacrylate Glue – Practical Tips

INDICATIONS:

  • Small corneal perforations ≤2 mm

  • Descemetocele

  • Impending perforation with localized thinning

  • Temporary tectonic support before definitive surgery

SURFACE PREPARATION:

  • Dry the corneal surface with a sterile wexcel sponge thoroughly before application

  • Even minimal surface moisture prevents proper polymerization

  • Apply the smallest possible amount using a 27–30G needle / cannula / insulin syringe tip

  • Thick blobs increase inflammation, discomfort, and premature dislodgement

  • Avoid intraocular seepage

  • Ensure the anterior chamber is well formed before application

  • If the AC is flat, reform first with air

  • Always place a bandage contact lens after glue application - reduces discomfort, prevents premature dislodgement, and improves patient tolerance

  • Keep the patient on a topical antibiotic to prevent secondary infection

WATCH FOR COMPLICATIONS:

  • Foreign body sensation

  • Secondary infection under the glue

  • Neovascularization and inflammation

  • Giant papillary conjunctivitis

  • Frequent follow-up is essential

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Image from Rajan Eye Care Hospital

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Thinning Post-CXL: How was it managed?