Posterior & Placoid - FFA & Other investigations

𝗔𝗣𝗠𝗣𝗣𝗘⁣ - 𝘐𝘯𝘷𝘦𝘴𝘵𝘪𝘨𝘢𝘵𝘪𝘰𝘯𝘴⁣

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● 𝗙𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗶𝗻 𝗔𝗻𝗴𝗶𝗼𝗴𝗿𝗮𝗺 (𝗙𝗔):​ 𝗘𝗮𝗿𝗹𝘆 𝗵𝘆𝗽𝗼𝗳𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝗰𝗲 (𝗯𝗹𝗼𝗰𝗸𝗮𝗴𝗲) 𝗰𝗼𝗿𝗿𝗲𝘀𝗽𝗼𝗻𝗱𝗶𝗻𝗴 𝘁𝗼 𝘁𝗵𝗲 𝗽𝗹𝗮𝗰𝗼𝗶𝗱 𝗹𝗲𝘀𝗶𝗼𝗻𝘀 𝗳𝗼𝗹𝗹𝗼𝘄𝗲𝗱 𝗯𝘆 𝗹𝗮𝘁𝗲, 𝗶𝗿𝗿𝗲𝗴𝘂𝗹𝗮𝗿 𝗵𝘆𝗽𝗲𝗿𝗳𝗹𝘂𝗼𝗿𝗲𝗰𝗲𝗻𝘁 𝘀𝘁𝗮𝗶𝗻𝗶𝗻𝗴⁣


● 𝘐𝘯𝘥𝘰𝘤𝘺𝘢𝘯𝘪𝘯𝘦 𝘎𝘳𝘦𝘦𝘯 (𝘐𝘊𝘎) 𝘈𝘯𝘨𝘪𝘰𝘨𝘳𝘢𝘮:​ Early and late hypofluorescence corresponding to the placoid lesions⁣

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● 𝘍𝘶𝘯𝘥𝘶𝘴 𝘢𝘶𝘵𝘰𝘧𝘭𝘰𝘶𝘳𝘦𝘴𝘤𝘦𝘯𝘴𝘦 (𝘍𝘈𝘍):​ Early and late hypoautoflourescence corresponding to the placoid lesions. Hypoautoflourescence may persist at borders after lesion resolution⁣

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● 𝘖𝘱𝘵𝘪𝘤𝘢𝘭 𝘤𝘰𝘩𝘦𝘳𝘦𝘯𝘤𝘦 𝘵𝘰𝘮𝘰𝘨𝘳𝘢𝘱𝘩𝘺 (𝘖𝘊𝘛):​ Hyperreflectivity from the outer plexiform layer to the RPE with normal retinal thickness in acute lesions. Hyperreflectivity of outer layers resolve along with resolution of the lesion. ⁣

In some cases, subretinal fluid can be seen. ⁣

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● CNS imaging ​should be performed to rule out CNS vasculitis in all patients with a new diagnosis of APMPPE.⁣

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𝘗𝘳𝘰𝘨𝘯𝘰𝘴𝘪𝘴 𝘢𝘯𝘥 𝘔𝘢𝘯𝘢𝘨𝘦𝘮𝘦𝘯𝘵⁣

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● Usually self-limiting with good prognosis⁣

● Risk factors for visual loss - foveal involvement at presentation, older age, unilateral disease, longer interval between initial and fellow eye involvement, recurrences⁣

● All patients with a new diagnosis of APMPPE should receive a full neurologic and systemic work-up to evaluate for CNS vasculitis and other associated systemic conditions⁣

● Role of steroids not fully understood⁣

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www.ophthalmobytes.com⁣

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