Posterior and placoid!


𝘈𝘤𝘶𝘵𝘦 𝘱𝘰𝘴𝘵𝘦𝘳𝘪𝘰𝘳 𝘮𝘶𝘭𝘵𝘪𝘧𝘰𝘤𝘢𝘭 𝘱𝘭𝘢𝘤𝘰𝘪𝘥 𝘱𝘪𝘨𝘮𝘦𝘯𝘵 𝘦𝘱𝘪𝘵𝘩𝘦𝘭𝘪𝘰𝘱𝘢𝘵𝘩𝘺 (𝘈𝘗𝘔𝘗𝘗𝘌)⁣





● White Dot Syndrome⁣

● Inflammatory chorioretinopathy which was first described by Gass in 1968.⁣

● Bilateral, M=F, 20-40 years⁣

● Association with HLAB7 and HLADR2,⁣

● Could be an immune driven vascular alteration⁣

𝘊𝘰𝘯𝘥𝘪𝘵𝘪𝘰𝘯𝘴 𝘢𝘴𝘴𝘰𝘤𝘪𝘢𝘵𝘦𝘥 𝘸𝘪𝘵𝘩 𝘈𝘗𝘔𝘗𝘗𝘌 ⁣

𝘐𝘯𝘧𝘦𝘤𝘵𝘪𝘰𝘶𝘴⁣

● Group A streptococcal⁣

● Adenovirus type 5⁣

● Tuberculosis⁣

● Lyme disease⁣

● Mumps⁣

● Hepatitis B vaccination⁣

𝘕𝘰𝘯𝘪𝘯𝘧𝘦𝘤𝘵𝘪𝘰𝘶𝘴⁣

● Erythema nodosum⁣

● Wegener granulomatosis⁣

● PAN⁣

● Cerebral vasculitis⁣

● Scleritis⁣

● Episcleritis⁣

● Sarcoidosis⁣

● Ulcerative colitis⁣

𝗦𝘆𝗺𝗽𝘁𝗼𝗺𝘀:⁣

● Preceding viral or flu like illness⁣

● Rapid onset of blurred vision bilaterally, and asymmetric⁣

● Fellow eye involved within days to weeks⁣

● Central and paracentral scotomas⁣

● Photopsias before vision loss⁣

● Headache and neurological symptoms⁣

𝗦𝗶𝗴𝗻𝘀:⁣

● VA 20/40- CF⁣

● Mild anterior uveitis⁣

● Mild to moderate vitritis 50%⁣

● 𝙁𝙪𝙣𝙙𝙪𝙨 - 𝙢𝙪𝙡𝙩𝙞𝙥𝙡𝙚 𝙛𝙡𝙖𝙩 𝙗𝙞𝙡𝙖𝙩𝙚𝙧𝙖𝙡 𝙮𝙚𝙡𝙡𝙤𝙬-𝙬𝙝𝙞𝙩𝙚 𝙥𝙡𝙖𝙘𝙤𝙞𝙙 𝙡𝙚𝙨𝙞𝙤𝙣𝙨 𝙖𝙩 𝙡𝙚𝙫𝙚𝙡 𝙤𝙛 𝙍𝙋𝙀 𝙖𝙣𝙙 𝙘𝙝𝙤𝙧𝙤𝙞𝙙 𝟷-𝟸 𝙙𝙞𝙨𝙘 𝙙𝙞𝙖𝙢𝙚𝙩𝙚𝙧𝙨 𝙥𝙤𝙨𝙩𝙚𝙧𝙞𝙤𝙧 𝙩𝙤 𝙚𝙦𝙪𝙖𝙩𝙤𝙧⁣

● New peripheral lesions can appear in a linear or radial array over the next 3 weeks⁣

● Papillitis seen, CME uncommon⁣

● Atypical findings- retinal vasculitis, RVOs, retinal neovascularization, exudative RDs⁣

● Fade over 1-2 weeks, resolves over 2-6 weeks⁣

● Older lesions --- well defined alteration in RPE consisting of alternating areas of depigmentation and hyperpigmentation due to pigment clumping⁣

● Variant - relentless placoid chorioretinitis - has features of APMPPE and serpiginous choroiditis⁣

Investigations and Management to follow soon. ⁣

www.ophthalmobytes.com⁣

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