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Meibomian Cyst!


Chalazion/ Meibomian Cyst!


-Gradually enlarging painless nodule.


PATHOPHYSIOLOGY:

-Meibomian gland secretions → blocked → retained oily secretions → breakdown of lipid possibly from bacterial enzymes or retained meibomian secretions → leak into adjacent tissue (surrounding tarsal plate stroma) → Chronic granulomatous inflammation of multinucleated giant cells and epithelioid cells surrounding a lipid globule (Lipogranuloma).


RISK FACTORS:

•Blepharitis

•Rosacea

•Seborrheic dermatitis

•Demodex mite infestation

•Low serum Vitamin A

•GI inflammation

•Smoking

•Diabetes


HISTOPATHOLOGY:

•Lipogranulomatous with extracellular fat deposits, epitheloid cells, multinucleated giant cells and lymphocytes.


ATYPICAL CHALAZIA:

•Do a biopsy to rule out neoplasms, infection (leishmaniasis/ TB masses), immune disorders (hyper IgE syndrome).


MANAGEMENT:


•Warm compress.

•Lid massage (to express the contents).

•Good lid hygiene.

•Oral Antibiotics (for significant bacterial infections).

•Intralesional injection of Triamcinalone.

•Incision & Curettage.


www.ophthalmobytes.com


Image from Rajan Eye Care Hospital #ophthalmology#ophthal#doctor#health#medical#vision#education#optometry#medicalstudent#optometrist#medicine#eye#ophtho#ophthalmologist#ophthalmo#med#medicaleducation#ophthalmologyresident#ophthalmologyresidency#apaoyo#eyelid#lid#chalazion

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