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'Glory'ous Morning!

𝐌𝐨𝐫𝐧𝐢𝐧𝐠 𝐆𝐥𝐨𝐫𝐲 𝐒𝐲𝐧𝐝𝐫𝐨𝐦𝐞⁣

● Rare congenital malformation of optic disc (1 in 10 million)⁣

● When associated with systemic signs and symptoms→ morning glory syndrome⁣

● Morphological similarity to the flower of the morning glory plant⁣

● Sporadic condition⁣

● More common in females⁣

𝘊𝘰𝘮𝘮𝘰𝘯 𝘴𝘺𝘴𝘵𝘦𝘮𝘪𝘤 𝘢𝘴𝘴𝘰𝘤𝘪𝘢𝘵𝘪𝘰𝘯𝘴:⁣

● Transsphenoidal basal encephalocele⁣

● Midfacial malformations⁣

● Others: Callosal agenesis, Hypoplasia of cerebral arteries, PHACE syndrome, Neurofibromatosis 2⁣

𝘚𝘪𝘨𝘯𝘴 𝘢𝘯𝘥 𝘴𝘺𝘮𝘱𝘵𝘰𝘮𝘴:⁣

● Visual acuity ranges from 20/20 to counting fingers depending on extent of optic nerve affected⁣

● Visual field defect: Enlarged blind spot⁣

● Associated Amblyopia, strabismus ⁣


● Usually unilateral⁣

● Large funnel shaped excavation in optic disc⁣

● White glial tissue occupying the central disc⁣

● Increased number of abnormally straight retinal blood vessels arise from disc margin and run radially towards peripheral fundus⁣

● Peripapillary chorioretinal pigmentation can be seen⁣

● Macular capture: When macula is involved in the excavation⁣

● Serous retinal detachment can occur in 30% (that tend to originate in peripapillary area and extend to posterior pole)⁣


● Optic disc coloboma⁣

● Peripapillary staphyloma⁣


● Management of amblyopia, strabismus⁣

● Observe for serous RDs⁣

● Brain imaging to rule out CNS involvement⁣

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