๐๐ค๐ถ๐ญ๐ข๐ณ ๐๐ถ๐ณ๐ง๐ข๐ค๐ฆ ๐๐ฒ๐ถ๐ข๐ฎ๐ฐ๐ถ๐ด ๐๐ฆ๐ฐ๐ฑ๐ญ๐ข๐ด๐ช๐ข (๐๐๐๐)โฃ โฃ Describes the entire spectrum of squamous neoplastic disease from dysplasia to carcinoma in situ and invasive SCCโฃ
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๐๐ก๐ซ๐๐ ๐ ๐ซ๐๐๐๐ฌ (๐๐๐ ๐๐ง๐ ๐๐ข๐ซ๐ฌ๐ญ):โฃ โฃ 1) Benign Dysplasia โฃ Papillomaโฃ Pseudoepitheliomatous hyperplasiaโฃ Benign hereditary intraepithelial dyskeratosisโฃ โฃ 2) Preinvasive OSSN โฃ Conjunctival/corneal carcinoma in situโฃ โฃ 3) Invasive OSSN โฃ Squamous carcinomaโฃ Mucoepidermoid carcinomaโฃ โฃ ๐๐ญ๐ข๐จ๐ฅ๐จ๐ ๐ข๐๐๐ฅ ๐๐๐๐ญ๐จ๐ซ๐ฌ:โฃ โฃ โ Old ageโฃ โ Ultraviolet B radiationโฃ โ Malesโฃ โ HPV infectionโฃ โ HIVโฃ โ Xeroderma pigmentosumโฃ โ Chemical exposureโฃ โ Cigarette smokingโฃ โ Vitamin A deficiencyโฃ โฃ ๐๐ฅ๐ข๐ง๐ข๐๐๐ฅ ๐ ๐๐๐ญ๐ฎ๐ซ๐๐ฌ:โฃ โฃ โ Most commonly in the interpalpebral area near the limbusโฃ โ Can extend across limbus to involve corneaโฃ โ Flat/Raised, pearly-gray or pink well-demarcated mass with feeder vesselsโฃ โ Fluorescein/lissamine/rose bengal stain used to highlight the lesionโฃ โฃ ๐๐จ๐ซ๐ฉ๐ก๐จ๐ฅ๐จ๐ ๐ข๐๐๐ฅ ๐๐ฒ๐ฉ๐๐ฌ:โฃ โฃ 1. ๐๐ญ๐ข๐ค๐ฐ๐ช๐ฅโฃ -Gelatinous : Commonest, placoid lesion with shiny velvety surface, and tufted vesselsโฃ -Papilliformโฃ -Velvetyโฃ -Leukoplakicโฃ โฃ 2. ๐๐ฐ๐ฅ๐ถ๐ญ๐ข๐ณ: Well circumscribed elevated focal mass with mulberry appearanceโฃ โฃ 3. ๐๐ช๐ง๐ง๐ถ๐ด๐ฆ variant: Shows radial growth pattern without well defined margin and may mimic chronic blepharoconjunctivitisโฃ โฃ Corneal involvement in OSSN gives a ground glass appearance with well defined borders or a beaten metal appearance on retroilluminationโฃ โฃ ๐๐ข๐๐ ๐ง๐จ๐ฌ๐ข๐ฌ:โฃ โฃ โ Histopathologyโฃ โ Impression Cytology โฃ โ AS OCTโฃ โ Confocal Microscopyโฃ โฃ ๐๐๐ง๐๐ ๐๐ฆ๐๐ง๐ญ:โฃ โฃ โ Surgical excision with wide margins and edge cryotherapyโฃ โ Chemotherapy (MMC/5FU)โฃ โ Radiotherapy (Ruthenium-106)โฃ โ Immunotherapy with Interferon alpha 2bโฃ โฃ www.ophthalmobytes.comโฃ โฃ Image from Rajan Eye Care Hospital #ophthalmology #ophthal #doctor #health #medical #vision #education #optometry #medicalstudent #optometrist #medicine #eye #ophtho #ophthalmologist #ophthalmo #med#med #medicaleducation#medicaleducation #ophthalmologyresident#ophthalmologyresident #ophthalmologyresidency#ophthalmologyresidency #ossn#ossn #ocularsurfacesquamousneoplasia#ocularsurfacesquamousneoplasia