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Arcus Senilis.


-Bilateral grey to white band of peripheral corneal opacification.


FEATURES:

-Bilateral.

-Fine dots with a clear zone between it and limbus (clear interval of Vogt).

-Diffuse central border with sharp peripheral border.

-Begins superiorly & inferiorly and involves entire periphery.

-Asymmetric in Unilateral Carotid vascular disease ( decreased arcus ) & chronic ocular hypotony (increased arcus)


LOCATION:

-Begins in DEEP STROMA with progression to superficial stroma.


COMPOSITION:

-Extracellular corticosteroid esters of lipoproteins of low density.

-Lipid material leaks from limbal capillaries with central flow being limited because of a functional barrier to the flow of large molecules on the cornea.


ARCUS JUVENILIS:

-Associated with increased plasma cholesterol and LDL levels in men younger than 50 years.

-Increased risk of mortality from CHD and Cardiovascular disease

-Increased risk for type 2a dyslipoproteinemia.


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