Rubeosis Iridis
Neovascularization of Iris (NVI)
New abnormal blood vessels on the surface of the iris in response to retinal ischemia
𝘊𝘰𝘮𝘮𝘰𝘯 𝘤𝘢𝘶𝘴𝘦𝘴:
● Advanced Proliferative Diabetic Retinopathy
● Central retinal vein occlusion
● Ocular ischemic syndrome
● Chronic retinal detachment
● Uveitis
● Neoplastic disorders eg. Retinoblastoma
● Post surgery (Vitrectomy/ Cataract Surgery)
● Trauma
𝐓𝐡𝐫𝐞𝐞 𝐬𝐭𝐚𝐠𝐞𝐬:
𝘚𝘵𝘢𝘨𝘦 𝟷:
● New thin walled vessels in iris near the pupillary border and at the root of iris
𝘚𝘵𝘢𝘨𝘦 𝟸:
● New vessels penetrate the anterior surface near pupil and root of iris- the two sets merge
● New vessels in iris stroma also
● Spontaneous hyphema can occur due to fragility of the blood vessels
𝘚𝘵𝘢𝘨𝘦 𝟹:
● Anterior surface fully covered by new vessels - becomes flat, loss of normal iris markings
● Ectropion uvea develops - anterior layer of new formed fibrovascular tissue contracts and pulls pigment layer anteriorly
● Peripheral anterior synechiae develops
● NVI may cover the trabecular meshwork - ultimately leads to neovascular glaucoma
Image from Rajan Eye Care Hospital
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